Synthesis of poly[2-(N,N-dimethyl)aminoethyl methacrylate-co-acrylonitrile]
نویسندگان
چکیده
منابع مشابه
Feedback-regulated paclitaxel delivery based on poly(N,N-dimethylaminoethyl methacrylate-co-2-hydroxyethyl methacrylate) nanoparticles.
pH-Sensitive poly(N,N-dimethylaminoethyl methacrylate (DMAEMA)/2-hydroxyethyl methacrylate (HEMA)) nanoparticles were prepared for the triggered release of paclitaxel within a tumor microenvironment. Tumors exhibit a lower extracellular pH than normal tissues. We show that paclitaxel release from DMAEMA/HEMA particles can be actively triggered by small, physiological changes in pH (within 0.2-0...
متن کاملSynthesis and Complexation of Well-Defined Labeled Poly(N,N-dimethylaminoethyl methacrylate)s (PDMAEMA)
We present the synthesis and characterization of well-defined polycationic copolymers containing thiazole dyes in the side chain. Atom transfer radical polymerization (ATRP) was used for the copolymerization of 3-azidopropyl methacrylate (AzPMA) and N,N-dimethylaminoethyl methacrylate (DMAEMA) of different composition. Thiazole-based alkyne-functionalized dyes (e.g., 5-methyl-4-(prop-2-yn-1-ylo...
متن کاملReducible Poly(2-dimethylaminoethyl) Methacrylate-Block-Polyvinylimidazole: Synthesis, Transfection Activity in Vitro
Reducible or imidazolyl polycations of block poly(imidazole/2-dimethylaminoethyl) are of promising in gene delivery. Dimeric poly(2-dimethylaminoethyl) methacrylate-block-polyvinylimidazole (rDPDMAEMAIM) and reducible poly (2-dimethylaminoethyl) methacrylate (rDPDMAEMA) with single disulfide bond in the backbone was synthesized by oxidizing their dithioester-terminated polymers. The polyplexes ...
متن کاملAtomistic simulation for coil-to-globule transition of poly(2-dimethylaminoethyl methacrylate).
The coil-to-globule transition of poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) in aqueous solution was investigated by all-atomistic molecular dynamics simulations. The polymer consistent force field (PCFF) was applied to the PDMAEMA model with a proper protonation state. The structural analysis indicates a distinct difference in the hydration state of particular functional groups of PDMAE...
متن کاملMagnetic Poly-(Acrylonitrile-Co-Acrylamide) Microparticles for Immobilization of Trypsin
Well-shaped spherical magnetic microspheres were prepared using a synthetic polymer of poly-(acrylonitrile-co-acrylamide). Their size varied from 100 up to 1000 μm proportionally to the flow rate of the polymer solution and their density was from 1030 to 1045 kg.m, depending on the magnetite content. Trypsin (EC 3.4.21.4) was chosen as model enzyme and immobilized on the acyl azide derivatives ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Polymer Bulletin
سال: 1995
ISSN: 0170-0839,1436-2449
DOI: 10.1007/bf00294961